Web13 jul. 2007 · The magnitude of diastereoselectivity of the alkylation was determined to be >10:1 after reductive removal of the auxiliary using lithium amidotrihydroborate (LAB). 12 The resulting primary alcohol 17 was then oxidized to the corresponding aldehyde under Swern conditions 13, which was subjected to Takai iodoolefination to give the (E)-vinyl … WebAndrew G. Myers graduated from MIT in 1981 with a Bachelor of Science degree. He was introduced to chemical research as an undergraduate in the laboratory of Professor …
Stereoselective Formation of Quaternary Carbon Centers
Web30 aug. 2009 · An advanced intermediate is cyclized to give the 14-membered macrocyclic core of 6-dEB using a late-stage (step 19 of 22) C–H oxidative macrolactonization reaction that proceeds with high regio-,... http://www.doczj.com/doc/443c69c008a1284ac85043f7.html binary quicksort
high-capacity hydrogen storage in lithium and sodium …
WebLithium Amidotrihydroborate, a Powerful New Reductant. Transformation of Tertiary Amides to Primary Alcohols. Citation Myers, Andrew G., Bryant Yang, and David Kopecky. 1996. … Web16 sep. 2024 · Reaction of the polymer-supported amines with excess n-butyllithium gave the corresponding lithium amide bases, which were tested in the aldol reactions of tropinone with benzaldehyde. The... Web31 jan. 2014 · Complete recovery of the staring material was observed. In contrast, lithium amidotrihydroborate affords mixtures of C–N/C–O cleavage products with similar substrates. 5d This divergent reactivity should prove useful in the selective reduction of this class of amides. Newcomb M. Tetrahedron 1993, 49, 1151. [Google Scholar] a. cyproheptadine and anxiety