Hepatocellularity翻译
Web12 sep. 2003 · Bayliss commented recently on hepatocellularity values, emphasizing the uncertainty of interspecies scaling and indicating that appropriate scaling factors remain to be clarified. Therefore, although the value of 120 × 10 6 cells per gram of liver has often been used in human IVIVE [ 18, 19 ], its accuracy in relation to interindividual differences … Webhepatocellularity - Wiktionary hepatocellularity English [ edit] Etymology [ edit] hepato- + cellularity Noun [ edit] hepatocellularity ( uncountable ) The condition of being hepatocellular This page was last edited on 11 March 2024, at 09:48. Text is available under the Creative Commons Attribution-ShareAlike License; additional terms may apply.
Hepatocellularity翻译
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Web1 jul. 2016 · For instance, when hepatocytes are used to predict hepatic drug clearance, the hepatocellularity (number of hepatocytes per gram liver, HPGL) is required as one of … WebScaling Factors for the Extrapolation of In Vivo Metabolic Drug Clearance From In Vitro Data: Reaching a Consensus on Values of Human Micro-somal Protein and …
Web美 [haɪpəseljʊ'lærɪtɪ] 是什么意思 释义 [医]细胞过多； 英英释义 hypercellularity n.the state of having abnormally many cells 学习怎么用 权威例句 hypercellularity hypercellularity Does …
WebMean geo hepatocellularity was 163 × 10 6 cells g −1 liver for Wistar rats (95% CI = 127–199 × 10 6 cells g −1 liver) and 169 × 10 6 cells g −1 liver (95% CI = 131–207 × 10 6 cells g −1 liver) for beagle dogs. The data generated in this study indicate a consistency in scaling factors between rat and dog. Web1 aug. 1997 · Microsomal protein recovery and hepatocellularity have been determined and investigated as scaling factors for interrelating clearance by hepatic microsomes, freshly isolated hepatocytes and whole liver from untreated (UT) rats and rats treated with either the cytochrome P450 inducer phenobarbital (PB) or dexamethasone (DEX).
Web1 feb. 2014 · Determination of the hepatocellularity number for human, dog, rabbit, rat and mouse livers from protein concentration measurements. Toxicol In Vitro (2006) L.T. Lee et al. Removal of unbound sodium dodecyl sulfate (SDS) from proteins in solution by electrophoresis through triton X-100-agarose.
Webhepatocellularity (3.1×109 cells per kilogram body weight, dotted line in Fig. 1)(27). Similar regression analyses for different datasets found that the empirical scaling factors necessary for accurate predictions were 5.2-fold (35) and 5.6-fold larger (45) than hepatocellularity (2.5–3.1×109 cells per stash honeydew teaWebMicrosomal protein per gram of liver (MPPGL) and hepatocellularity number per gram of liver (HPGL) using CYP P450 content method ranged 41–73 mg/gram of liver (mean= 57 … stash hotels loginWeb28 jan. 2010 · Sandwich-cultured hepatocytes (SCH) are a powerful in vitro tool that can be utilized to study hepatobiliary drug transport, species differences in drug transport, transport protein regulation, drug-drug interactions, and hepatotoxicity. stash honey sticksWebhepatocellular 音标：/ˌhepətəu'seljulə/ 全球发音： 生词本： 添加笔记： 有奖纠错 划词 英汉-汉英词典 词组搭配 英语例句库 全文检索 英汉-汉英词典 adj. 细胞的 词组 习惯用语 … stash hotels locationsWebWilson ZE, Rostami-Hodjegan A, Burn JL, Tooley A, Boyle J, Ellis SW, Tucker GT. Inter-individual variability in levels of human microsomal protein and hepatocellularity per gram of liver. Br J Clin Pharmacol. 2003 Oct56(4):433-40. abstract PubMed ID 12968989: Method stash hotelsWeb11 aug. 2008 · Trout hepatocellularity Based on the principle that hepatocytes represent almost the same protein content in liver as in the isolated cells (Worboys et al., 1996), the value for H T can be obtained from the ratio between the protein concentrations in liver homogenates ( P L ) and in hepatocyte suspensions ( P H , Eq. stash house broken arrowWebVALUES OF HUMAN HEPATOCELLULARITY PER GRAM OF LIVER AND ASSOCIATED VARIABILITY FOR USE IN THE PREDICTION OF HUMAN IN VIVO METABOLIC … stash homes